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Targeting the BspC-vimentin interaction to develop anti-virulence therapies during Group B streptococcal meningitis

Bacterial infections are a major cause of morbidity and mortality worldwide and the rise of antibiotic resistance necessitates development of alternative treatments. Pathogen adhesins that bind to host cells initiate disease pathogenesis and represent potential therapeutic targets. We have shown pre...

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Detalles Bibliográficos
Autores principales: Manzer, Haider S., Villarreal, Ricardo I., Doran, Kelly S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939794/
https://www.ncbi.nlm.nih.gov/pubmed/35316308
http://dx.doi.org/10.1371/journal.ppat.1010397