Cargando…
Targeting the BspC-vimentin interaction to develop anti-virulence therapies during Group B streptococcal meningitis
Bacterial infections are a major cause of morbidity and mortality worldwide and the rise of antibiotic resistance necessitates development of alternative treatments. Pathogen adhesins that bind to host cells initiate disease pathogenesis and represent potential therapeutic targets. We have shown pre...
Autores principales: | Manzer, Haider S., Villarreal, Ricardo I., Doran, Kelly S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939794/ https://www.ncbi.nlm.nih.gov/pubmed/35316308 http://dx.doi.org/10.1371/journal.ppat.1010397 |
Ejemplares similares
-
The Group B Streptococcal Adhesin BspC Interacts with Host Cytokeratin 19 To Promote Colonization of the Female Reproductive Tract
por: Manzer, Haider S., et al.
Publicado: (2022) -
The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis
por: Deng, Liwen, et al.
Publicado: (2019) -
The Multifaceted Nature of Streptococcal Antigen I/II Proteins in Colonization and Disease Pathogenesis
por: Manzer, Haider S., et al.
Publicado: (2020) -
Identification of a novel cationic glycolipid in Streptococcus agalactiae that contributes to brain entry and meningitis
por: Joyce, Luke R., et al.
Publicado: (2022) -
Identification of CiaR Regulated Genes That Promote Group B Streptococcal Virulence and Interaction with Brain Endothelial Cells
por: Mu, Rong, et al.
Publicado: (2016)