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mTOR activity is essential for retinal pigment epithelium regeneration in zebrafish

The retinal pigment epithelium (RPE) plays numerous critical roles in maintaining vision and this is underscored by the prevalence of degenerative blinding diseases like age-related macular degeneration (AMD), in which visual impairment is caused by progressive loss of RPE cells. In contrast to mamm...

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Detalles Bibliográficos
Autores principales: Lu, Fangfang, Leach, Lyndsay L., Gross, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939802/
https://www.ncbi.nlm.nih.gov/pubmed/35271573
http://dx.doi.org/10.1371/journal.pgen.1009628