Sustained chemogenetic activation of locus coeruleus norepinephrine neurons promotes dopaminergic neuron survival in synucleinopathy

Dopaminergic neuron degeneration in the midbrain plays a pivotal role in motor symptoms associated with Parkinson’s disease. However, non-motor symptoms of Parkinson’s disease and post-mortem histopathology confirm dysfunction in other brain areas, including the locus coeruleus and its associated ne...

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Detalles Bibliográficos
Autores principales: Jovanovic, Predrag, Wang, Yidan, Vit, Jean-Philippe, Novinbakht, Edward, Morones, Nancy, Hogg, Elliot, Tagliati, Michele, Riera, Celine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939823/
https://www.ncbi.nlm.nih.gov/pubmed/35316276
http://dx.doi.org/10.1371/journal.pone.0263074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939823/
https://www.ncbi.nlm.nih.gov/pubmed/35316276
http://dx.doi.org/10.1371/journal.pone.0263074

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