Efficacy of PEGylated ciliary neurotrophic factor superagonist variant in diet-induced obesity mice

Ciliary neurotrophic factor (CNTF) is a neurotrophic cytokine able to induce appetite reduction, weight loss and antidiabetic effects. However, its susceptibility to neutralizing anti-CNTF antibodies in patients hampered its use for treatment of human obesity and diabetes. In addition, CNTF has a ve...

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Detalles Bibliográficos
Autores principales: Battista, Maria Rosaria, Grigoletto, Antonella, Tedeschini, Tommaso, Cellucci, Antonella, Colaceci, Fabrizio, Laufer, Ralph, Pasut, Gianfranco, Di Marco, Annalise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939829/
https://www.ncbi.nlm.nih.gov/pubmed/35316287
http://dx.doi.org/10.1371/journal.pone.0265749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939829/
https://www.ncbi.nlm.nih.gov/pubmed/35316287
http://dx.doi.org/10.1371/journal.pone.0265749

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