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Mast cell granule motility and exocytosis is driven by dynamic microtubule formation and kinesin-1 motor function

Mast cells are tissue-resident immune cells that have numerous cytoplasmic granules which contain preformed pro-inflammatory mediators. Upon antigen stimulation, sensitized mast cells undergo profound changes to their morphology and rapidly release granule mediators by regulated exocytosis, also kno...

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Detalles Bibliográficos
Autores principales: Ibanga, Jeremies, Zhang, Eric L., Eitzen, Gary, Guo, Yitian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939832/
https://www.ncbi.nlm.nih.gov/pubmed/35316306
http://dx.doi.org/10.1371/journal.pone.0265122