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Gamma-oryzanol reduces renal inflammation and oxidative stress by modulating AGEs/RAGE axis in animals submitted to high sugar-fat diet

INTRODUCTION: The receptor for AGEs (RAGE) is a multiligand member of the immunoglobulin superfamily of cell surface receptors expressed in many organs, among them, the kidneys. When activated, RAGE leads to a sequence of signaling that results in inflammation and oxidative stress, both involved in...

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Detalles Bibliográficos
Autores principales: Francisqueti-Ferron, Fabiane Valentini, Ferron, Artur Junio Togneri, Altomare, Alessandra, Garcia, Jéssica Leite, Moreto, Fernando, Ferreira, Ana Lúcia A., Minatel, Igor Otávio, Aldini, Giancarlo, Corrêa, Camila Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Nefrologia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940121/
https://www.ncbi.nlm.nih.gov/pubmed/34174064
http://dx.doi.org/10.1590/2175-8239-JBN-2021-0002