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Intravitreal Administration of rhNGF Enhances Regenerative Processes in a Zebrafish Model of Retinal Degeneration

Nerve growth factor (NGF) is the best characterized neurotrophin, and it is known to play an important role in ocular homeostasis. Here, we demonstrated the expression of NGF receptors in adult zebrafish retina and optimized a light-induced retina degeneration (LID) zebrafish model that mimics human...

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Detalles Bibliográficos
Autores principales: Cocchiaro, Pasquale, Di Donato, Vincenzo, Rubbini, Davide, Mastropasqua, Rodolfo, Allegretti, Marcello, Mantelli, Flavio, Aramini, Andrea, Brandolini, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940169/
https://www.ncbi.nlm.nih.gov/pubmed/35330834
http://dx.doi.org/10.3389/fphar.2022.822359