Targeted Gene Insertion for Functional CFTR Restoration in Airway Epithelium

Cystic Fibrosis (CF) is caused by a diverse set of mutations distributed across the approximately 250 thousand base pairs of the CFTR gene locus, of which at least 382 are disease-causing (CFTR2.org). Although a variety of editing tools are now available for correction of individual mutations, a str...

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Detalles Bibliográficos
Autores principales: Barillà, Cristina, Suzuki, Shingo, Rab, Andras, Sorscher, Eric J., Davis, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genome Editing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940244/
https://www.ncbi.nlm.nih.gov/pubmed/35330693
http://dx.doi.org/10.3389/fgeed.2022.847645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940244/
https://www.ncbi.nlm.nih.gov/pubmed/35330693
http://dx.doi.org/10.3389/fgeed.2022.847645

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