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Integration of omics data to generate and analyse COVID-19 specific genome-scale metabolic models

COVID-19 presents a complex disease that needs to be addressed using systems medicine approaches that include genome-scale metabolic models (GEMs). Previous studies have used a single model extraction method (MEM) and/or a single transcriptomic dataset to reconstruct context-specific models, which p...

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Detalles Bibliográficos
Autores principales: Režen, Tadeja, Martins, Alexandre, Mraz, Miha, Zimic, Nikolaj, Rozman, Damjana, Moškon, Miha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940269/
https://www.ncbi.nlm.nih.gov/pubmed/35339845
http://dx.doi.org/10.1016/j.compbiomed.2022.105428