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High Levels of Cerebrospinal Fluid Kappa Free Light Chains Relate to IgM Intrathecal Synthesis and Might Have Prognostic Implications in Relapsing Multiple Sclerosis

Cerebrospinal kappa free light chain (KFLC)-index is a marker of intrathecal immunoglobulin synthesis that aids in the diagnosis of multiple sclerosis (MS). However, little evidence exists on its prognostic role. Our aim is to analyze the relationship between KFLC-index and other MS biomarkers and t...

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Detalles Bibliográficos
Autores principales: Castillo-Villalba, Jéssica, Gil-Perotín, Sara, Gasque-Rubio, Raquel, Cubas-Nuñez, Laura, Carratalà-Boscà, Sara, Alcalá, Carmen, Quintanilla-Bordás, Carlos, Pérez-Miralles, Francisco, Ferrer, Cristina, Cañada Martínez, Antonio, Tortosa, Jordi, Solís-Tarazona, Luís, Campos, Luisa, Leivas, Alberto, Laíz Marro, Begoña, Casanova, Bonaventura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940299/
https://www.ncbi.nlm.nih.gov/pubmed/35330910
http://dx.doi.org/10.3389/fimmu.2022.827738