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Capture Sequencing Enables Sensitive Detection of Tick-Borne Agents in Human Blood

Assay sensitivity can be a limiting factor in the use of PCR as a tool for the detection of tick-borne pathogens in blood. We evaluated the performance of Tick-borne disease Capture Sequencing Assay (TBDCapSeq), a capture sequencing assay targeting tick-borne agents, to test 158 whole blood specimen...

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Detalles Bibliográficos
Autores principales: Sanchez-Vicente, Santiago, Jain, Komal, Tagliafierro, Teresa, Gokden, Alper, Kapoor, Vishal, Guo, Cheng, Horn, Elizabeth J., Lipkin, W. Ian, Tokarz, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940530/
https://www.ncbi.nlm.nih.gov/pubmed/35330765
http://dx.doi.org/10.3389/fmicb.2022.837621