Multi-arm RNA junctions encoding molecular logic unconstrained by input sequence for versatile cell-free diagnostics

Applications of RNA-based molecular logic have been hampered by sequence constraints imposed on the input and output of the circuits. Here we show that the sequence constraints can be substantially reduced by appropriately encoded multi-arm junctions of single-stranded RNA structures. To conditional...

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Detalles Bibliográficos
Autores principales: Ma, Duo, Li, Yuexin, Wu, Kaiyue, Yan, Zhaoqing, Tang, Anli A., Chaudhary, Soma, Ticktin, Zachary M., Alcantar-Fernandez, Jonathan, Moreno-Camacho, José L., Campos-Romero, Abraham, Green, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940621/
https://www.ncbi.nlm.nih.gov/pubmed/35288660
http://dx.doi.org/10.1038/s41551-022-00857-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940621/
https://www.ncbi.nlm.nih.gov/pubmed/35288660
http://dx.doi.org/10.1038/s41551-022-00857-7

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