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Multi-arm RNA junctions encoding molecular logic unconstrained by input sequence for versatile cell-free diagnostics
Applications of RNA-based molecular logic have been hampered by sequence constraints imposed on the input and output of the circuits. Here we show that the sequence constraints can be substantially reduced by appropriately encoded multi-arm junctions of single-stranded RNA structures. To conditional...
Autores principales: | Ma, Duo, Li, Yuexin, Wu, Kaiyue, Yan, Zhaoqing, Tang, Anli A., Chaudhary, Soma, Ticktin, Zachary M., Alcantar-Fernandez, Jonathan, Moreno-Camacho, José L., Campos-Romero, Abraham, Green, Alexander A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940621/ https://www.ncbi.nlm.nih.gov/pubmed/35288660 http://dx.doi.org/10.1038/s41551-022-00857-7 |
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