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Association of Retromer Deficiency and Tau Pathology in Down Syndrome
Retromer deficiency is reported in Down syndrome and correlates with amyloidosis, however, its association with tau neuropathology remains unclear. Down syndrome and control brain tissues were evaluated for phosphorylated tau, tau modulators, and cathepsin‐D activity. Several kinases and phosphatase...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940634/ https://www.ncbi.nlm.nih.gov/pubmed/35150166 http://dx.doi.org/10.1002/ana.26321 |