Exposure-response modeling improves selection of radiation and radiosensitizer combinations

A central question in drug discovery is how to select drug candidates from a large number of available compounds. This analysis presents a model-based approach for comparing and ranking combinations of radiation and radiosensitizers. The approach is quantitative and based on the previously-derived T...

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Detalles Bibliográficos
Autores principales: Cardilin, Tim, Almquist, Joachim, Jirstrand, Mats, Zimmermann, Astrid, Lignet, Floriane, El Bawab, Samer, Gabrielsson, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940791/
https://www.ncbi.nlm.nih.gov/pubmed/34623558
http://dx.doi.org/10.1007/s10928-021-09784-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940791/
https://www.ncbi.nlm.nih.gov/pubmed/34623558
http://dx.doi.org/10.1007/s10928-021-09784-7

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