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Population pharmacokinetic model selection assisted by machine learning

A fit-for-purpose structural and statistical model is the first major requirement in population pharmacometric model development. In this manuscript we discuss how this complex and computationally intensive task could benefit from supervised machine learning algorithms. We compared the classical pha...

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Detalles Bibliográficos
Autores principales: Sibieude, Emeric, Khandelwal, Akash, Girard, Pascal, Hesthaven, Jan S., Terranova, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940812/
https://www.ncbi.nlm.nih.gov/pubmed/34708337
http://dx.doi.org/10.1007/s10928-021-09793-6