Pre-activation of autophagy impacts response to olaparib in prostate cancer cells

Poly (ADP-ribose) polymerase 1 (PARP1) plays an essential role in DNA repair and is targeted by anticancer therapies using PARP inhibitors (PARPi) such as olaparib. PARPi treatment in prostate cancer (PC) is currently used as a monotherapy or in combination with standard therapies (hormonotherapy) i...

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Detalles Bibliográficos
Autores principales: Cahuzac, Maxime, Langlois, Patricia, Péant, Benjamin, Fleury, Hubert, Mes-Masson, Anne-Marie, Saad, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940895/
https://www.ncbi.nlm.nih.gov/pubmed/35318456
http://dx.doi.org/10.1038/s42003-022-03210-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940895/
https://www.ncbi.nlm.nih.gov/pubmed/35318456
http://dx.doi.org/10.1038/s42003-022-03210-5

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