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Expanding the chemical space of 3(5)-functionalized 1,2,4-triazoles

[Image: see text] An efficient approach to the gram-scale synthesis of 3(5)-substituted, 1,3- and 1,5-disubstituted 1,2,4-triazole-derived building blocks is described. The key synthetic precursors – 1,2,4-triazole-3(5)-carboxylates (20 examples, 35–89% yield) were prepared from readily available ac...

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Detalles Bibliográficos
Autores principales: Khomenko, Dmytro M., Doroshchuk, Roman O., Ohorodnik, Yulia M., Ivanova, Hanna V., Zakharchenko, Borys V., Raspertova, Ilona V., Vaschenko, Oleksandr V., Dobrydnev, Alexey V., Grygorenko, Oleksandr O., Lampeka, Rostyslav D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8940976/
https://www.ncbi.nlm.nih.gov/pubmed/35340781
http://dx.doi.org/10.1007/s10593-022-03064-z