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Anti-CD80/86 antibodies inhibit inflammatory reaction and improve graft survival in a high-risk murine corneal transplantation rejection model

We investigated the effects of anti-CD80/86 antibodies in a murine high-risk corneal transplantation rejection model. A mixed lymphocyte reaction (MLR) assay was conducted with anti-CD80/86 antibodies. Inflammatory cytokine levels in the culture supernatant were measured using an enzyme-linked immun...

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Detalles Bibliográficos
Autores principales: Zhu, Jun, Inomata, Takenori, Nakamura, Masahiro, Fujimoto, Keiichi, Akasaki, Yasutsugu, Fujio, Kenta, Yanagawa, Ai, Uchida, Koichiro, Sung, Jaemyoung, Negishi, Naoko, Nagino, Ken, Okumura, Yuichi, Miura, Maria, Shokirova, Hurramhon, Kuwahara, Mizu, Hirosawa, Kunihiko, Midorikawa-Inomata, Akie, Eguchi, Atsuko, Huang, Tianxiang, Yagita, Hideo, Habu, Sonoko, Okumura, Ko, Murakami, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941080/
https://www.ncbi.nlm.nih.gov/pubmed/35318419
http://dx.doi.org/10.1038/s41598-022-08949-9