In vivo imaging with two-photon microscopy to assess the tumor-selective binding of an anti-CD137 switch antibody

STA551, a novel anti-CD137 switch antibody, binds to CD137 in an extracellular ATP concentration-dependent manner. Although STA551 is assumed to show higher target binding in tumor tissues than in normal tissues, quantitative detection of the target binding of the switch antibody in vivo is technica...

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Detalles Bibliográficos
Autores principales: Kaneko, Chisato, Tsutsui, Haruka, Ozeki, Kazuhisa, Honda, Masaki, Haraya, Kenta, Narita, Yoshinori, Kamata-Sakurai, Mika, Kikuta, Junichi, Tabo, Mitsuyasu, Ishii, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941111/
https://www.ncbi.nlm.nih.gov/pubmed/35318394
http://dx.doi.org/10.1038/s41598-022-08951-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941111/
https://www.ncbi.nlm.nih.gov/pubmed/35318394
http://dx.doi.org/10.1038/s41598-022-08951-1

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