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In vivo imaging with two-photon microscopy to assess the tumor-selective binding of an anti-CD137 switch antibody
STA551, a novel anti-CD137 switch antibody, binds to CD137 in an extracellular ATP concentration-dependent manner. Although STA551 is assumed to show higher target binding in tumor tissues than in normal tissues, quantitative detection of the target binding of the switch antibody in vivo is technica...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941111/ https://www.ncbi.nlm.nih.gov/pubmed/35318394 http://dx.doi.org/10.1038/s41598-022-08951-1 |