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Interferon-γ signal drives differentiation of T-bet(hi) atypical memory B cells into plasma cells following Plasmodium vivax infection

For development of a long-lasting protective malaria vaccine, it is crucial to understand whether Plasmodium-induced memory B cells (MBCs) or plasma cells develop and stably contribute to protective immunity, or on the contrary the parasite suppresses antibody responses by inducing MBC dysfunction....

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Detalles Bibliográficos
Autores principales: Kochayoo, Piyawan, Thawornpan, Pongsakorn, Wangriatisak, Kittikorn, Changrob, Siriruk, Leepiyasakulchai, Chaniya, Khowawisetsut, Ladawan, Adams, John H., Chootong, Patchanee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941117/
https://www.ncbi.nlm.nih.gov/pubmed/35318412
http://dx.doi.org/10.1038/s41598-022-08976-6