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Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5/6 nephrectomy-induced CKD rat model

Ferroptosis is a non-traditional form of regulated cell death, characterized by iron overload and lipid peroxidation. Exploration of ferroptosis in chronic kidney disease (CKD) has been extremely limited to date. In this study, we established a rat model of CKD by 5/6 nephrectomy, treated CKD rats w...

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Detalles Bibliográficos
Autores principales: Wang, Jingyu, Wang, Yaqing, Liu, Yi, Cai, Xintian, Huang, Xin, Fu, Wenjing, Wang, Lei, Qiu, Lihua, Li, Junying, Sun, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941123/
https://www.ncbi.nlm.nih.gov/pubmed/35318301
http://dx.doi.org/10.1038/s41420-022-00931-8