Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors

Rhabdoid tumors (RT) are rare and highly aggressive pediatric neoplasms. Their epigenetically-driven intertumoral heterogeneity is well described; however, the cellular origin of RT remains an enigma. Here, we establish and characterize different genetically engineered mouse models driven under the...

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Detalles Bibliográficos
Autores principales: Graf, Monika, Interlandi, Marta, Moreno, Natalia, Holdhof, Dörthe, Göbel, Carolin, Melcher, Viktoria, Mertins, Julius, Albert, Thomas K., Kastrati, Dennis, Alfert, Amelie, Holsten, Till, de Faria, Flavia, Meisterernst, Michael, Rossig, Claudia, Warmuth-Metz, Monika, Nowak, Johannes, Meyer zu Hörste, Gerd, Mayère, Chloe, Nef, Serge, Johann, Pascal, Frühwald, Michael C., Dugas, Martin, Schüller, Ulrich, Kerl, Kornelius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941154/
https://www.ncbi.nlm.nih.gov/pubmed/35318328
http://dx.doi.org/10.1038/s41467-022-29152-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941154/
https://www.ncbi.nlm.nih.gov/pubmed/35318328
http://dx.doi.org/10.1038/s41467-022-29152-4

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