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Dual-functional porous and cisplatin-loaded polymethylmethacrylate cement for reconstruction of load-bearing bone defect kills bone tumor cells

Malignant bone tumors are usually treated by resection of tumor tissue followed by filling of the bone defect with bone graft substitutes. Polymethylmethacrylate (PMMA) cement is the most commonly used bone substitute in clinical orthopedics in view of its reliability. However, the dense nature of P...

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Detalles Bibliográficos
Autores principales: Wang, Zhule, Nogueira, Liebert Parreiras, Haugen, Håvard Jostein, Van Der Geest, Ingrid CM., de Almeida Rodrigues, Patricia Caetano, Janssen, Dennis, Bitter, Thom, van den Beucken, Jeroen J.J.P., Leeuwenburgh, Sander CG.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941180/
https://www.ncbi.nlm.nih.gov/pubmed/35386344
http://dx.doi.org/10.1016/j.bioactmat.2021.12.023