Cargando…

Gut neurotoxin p-cresol induces brain-derived neurotrophic factor secretion and increases the expression of neurofilament subunits in PC-12 cells

Increased p-cresol levels reportedly alter brain dopamine metabolism and exacerbate neurological disorders in experimental animals. In contrast to toxic concentrations, low doses of p-cresol may have distinct effects on neuronal metabolism. However, the role of p-cresol in synapse remodeling, neurit...

Descripción completa

Detalles Bibliográficos
Autores principales: Tevzadze, Gigi, Barbakadze, Tamar, Kvergelidze, Elisabed, Zhuravliova, Elene, Shanshiashvili, Lali, Mikeladze, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIMS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941194/
https://www.ncbi.nlm.nih.gov/pubmed/35434277
http://dx.doi.org/10.3934/Neuroscience.2022002