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Gut neurotoxin p-cresol induces brain-derived neurotrophic factor secretion and increases the expression of neurofilament subunits in PC-12 cells
Increased p-cresol levels reportedly alter brain dopamine metabolism and exacerbate neurological disorders in experimental animals. In contrast to toxic concentrations, low doses of p-cresol may have distinct effects on neuronal metabolism. However, the role of p-cresol in synapse remodeling, neurit...
Autores principales: | Tevzadze, Gigi, Barbakadze, Tamar, Kvergelidze, Elisabed, Zhuravliova, Elene, Shanshiashvili, Lali, Mikeladze, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIMS Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941194/ https://www.ncbi.nlm.nih.gov/pubmed/35434277 http://dx.doi.org/10.3934/Neuroscience.2022002 |
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