Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells

Elevated fasting blood glucose (FBG) is associated with increased risks of developing type 2 diabetes (T2D) and cardiovascular-associated mortality. G6PC2 is predominantly expressed in islets, encodes a glucose-6-phosphatase catalytic subunit that converts glucose-6-phosphate (G6P) to glucose, and h...

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Detalles Bibliográficos
Autores principales: Rahim, Mohsin, Nakhe, Arya Y., Banerjee, Deveena R., Overway, Emily M., Bosma, Karin J., Rosch, Jonah C., Oeser, James K., Wang, Bo, Lippmann, Ethan S., Jacobson, David A., O'Brien, Richard M., Young, Jamey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941207/
https://www.ncbi.nlm.nih.gov/pubmed/35176280
http://dx.doi.org/10.1016/j.jbc.2022.101729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941207/
https://www.ncbi.nlm.nih.gov/pubmed/35176280
http://dx.doi.org/10.1016/j.jbc.2022.101729

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