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Proteomics Profiling of Human Synovial Fluid Suggests Increased Protein Interplay in Early-Osteoarthritis (OA) That Is Lost in Late-Stage OA

The underlying molecular mechanisms in osteoarthritis (OA) development are largely unknown. This study explores the proteome and the pairwise interplay of proteins in synovial fluid from patients with late-stage knee OA (arthroplasty), early knee OA (arthroscopy due to degenerative meniscal tear), a...

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Detalles Bibliográficos
Autores principales: Ali, Neserin, Turkiewicz, Aleksandra, Hughes, Velocity, Folkesson, Elin, Tjörnstand, Jon, Neuman, Paul, Önnerfjord, Patrik, Englund, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941261/
https://www.ncbi.nlm.nih.gov/pubmed/35074580
http://dx.doi.org/10.1016/j.mcpro.2022.100200