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Modelling the genetic aetiology of complex disease: human–mouse conservation of noncoding features and disease-associated loci
Understanding the genetic aetiology of loci associated with a disease is crucial for developing preventative measures and effective treatments. Mouse models are used extensively to understand human pathobiology and mechanistic functions of disease-associated loci. However, the utility of mouse model...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941414/ https://www.ncbi.nlm.nih.gov/pubmed/35317627 http://dx.doi.org/10.1098/rsbl.2021.0630 |