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The bacterial microbiota regulates normal hematopoiesis via metabolite-induced type 1 interferon signaling

Antibiotic therapy, especially when administered long term, is associated with adverse hematologic effects such as cytopenia. Signals from the intestinal microbiota are critical to maintain normal hematopoiesis, and antibiotics can cause bone marrow suppression through depletion of the microbiota. W...

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Detalles Bibliográficos
Autores principales: Yan, Hannah, Walker, Forrest C., Ali, Arushana, Han, Hyojeong, Tan, Lin, Veillon, Lucas, Lorenzi, Philip L., Baldridge, Megan T., King, Katherine Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941453/
https://www.ncbi.nlm.nih.gov/pubmed/35143611
http://dx.doi.org/10.1182/bloodadvances.2021006816