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Lysosomal iron recycling in mouse macrophages is dependent upon both LcytB and Steap3 reductases
Iron that is stored in macrophages as ferritin can be made bioavailable by degrading ferritin in the lysosome and releasing iron back into the cytosol. Iron stored in ferritin is found as Fe(3+) and must be reduced to Fe(2+) before it can be exported from the lysosome. Here we report that the lysoso...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Hematology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941456/ https://www.ncbi.nlm.nih.gov/pubmed/34982827 http://dx.doi.org/10.1182/bloodadvances.2021005609 |