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Prevalence and variation of CHIP in patients with aggressive lymphomas undergoing CD19-directed CAR T-cell treatment

Inflammation plays an important role in chimeric antigen receptor (CAR) T-cell therapy, especially in the pathophysiology of cytokine-release syndrome (CRS) and immune effector cell–associated neurotoxicity syndrome (ICANS). Clonal hematopoiesis of indetermined potential (CHIP) has also been associa...

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Detalles Bibliográficos
Autores principales: Teipel, Raphael, Kroschinsky, Frank, Kramer, Michael, Kretschmann, Theresa, Egger-Heidrich, Katharina, Krüger, Thomas, Ruhnke, Leo, Herold, Sylvia, Stasik, Sebastian, Sockel, Katja, Middeke, Jan M., Trautmann-Grill, Karolin, Bornhäuser, Martin, Thiede, Christian, von Bonin, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941459/
https://www.ncbi.nlm.nih.gov/pubmed/35008107
http://dx.doi.org/10.1182/bloodadvances.2021005747