Deleterious effect of bone marrow-resident macrophages on hematopoietic stem cells in response to total body irradiation

Bone marrow (BM) resident macrophages interact with a population of long-term hematopoietic stem cells (LT-HSCs) but their role on LT-HSC properties after stress is not well defined. Here, we show that a 2 Gy-total body irradiation (TBI)-mediated death of LT-HSCs is associated with increased percent...

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Detalles Bibliográficos
Autores principales: Chalot, Marion, Barroca, Vilma, Devanand, Saiyirami, Hoffschir, Françoise, Romeo, Paul-Henri, Moreno, Stéphanie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Hematopoiesis and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941479/
https://www.ncbi.nlm.nih.gov/pubmed/35100346
http://dx.doi.org/10.1182/bloodadvances.2021005983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941479/
https://www.ncbi.nlm.nih.gov/pubmed/35100346
http://dx.doi.org/10.1182/bloodadvances.2021005983

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