KLF4 downregulates FGF21 to activate inflammatory injury and oxidative stress of LPS-induced ATDC5 cells via SIRT1/NF-κB/p53 signaling

Ankylosing spondylitis (AS) is a chronic inflammatory disease. Transcriptional regulation of fibroblast growth factor 21 (FGF21) by the transcription factor Krüppel-like factor 4 (KLF4) serves an important role in chronic inflammatory disease. However, to the best of our knowledge, the role of both...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Wen, Jia, Liu, Chaoqi, Guo, Donggeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941512/
https://www.ncbi.nlm.nih.gov/pubmed/35293599
http://dx.doi.org/10.3892/mmr.2022.12680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941512/
https://www.ncbi.nlm.nih.gov/pubmed/35293599
http://dx.doi.org/10.3892/mmr.2022.12680

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