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SESN1 attenuates the Ox-LDL-induced inflammation, apoptosis and endothelial-mesenchymal transition of human umbilical vein endothelial cells by regulating AMPK/SIRT1/LOX1 signaling

Endothelial cells are an important component of the heart and vasculature and form a crucial link between the cardiovascular system and the immune system. Sestrin 1 (SESN1) has an important role in atherosclerosis by inhibiting NOD-like receptor family pyrin domain containing 3 inflammasome activati...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Zhao, Yongcheng, Zhang, Bin, Xiao, Chunwei, Sun, Zhanfa, Gao, Yuan, Dou, Xueyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941522/
https://www.ncbi.nlm.nih.gov/pubmed/35293601
http://dx.doi.org/10.3892/mmr.2022.12678