Cargando…

SESN1 attenuates the Ox-LDL-induced inflammation, apoptosis and endothelial-mesenchymal transition of human umbilical vein endothelial cells by regulating AMPK/SIRT1/LOX1 signaling

Endothelial cells are an important component of the heart and vasculature and form a crucial link between the cardiovascular system and the immune system. Sestrin 1 (SESN1) has an important role in atherosclerosis by inhibiting NOD-like receptor family pyrin domain containing 3 inflammasome activati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Feng, Zhao, Yongcheng, Zhang, Bin, Xiao, Chunwei, Sun, Zhanfa, Gao, Yuan, Dou, Xueyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941522/ https://www.ncbi.nlm.nih.gov/pubmed/35293601 http://dx.doi.org/10.3892/mmr.2022.12678

Ejemplares similares

Regulation of endothelial ferroptosis by SESN1 in atherosclerosis and its related mechanism
por: Gao, Feng, et al.
Publicado: (2023)

LOX-1, OxLDL, and Atherosclerosis
por: Pirillo, Angela, et al.
Publicado: (2013)

Metformin regulates oxLDL-facilitated endothelial dysfunction by modulation of SIRT1 through repressing LOX-1-modulated oxidative signaling
por: Hung, Ching-Hsia, et al.
Publicado: (2016)

Ox-LDL increases OX40L in endothelial cells through a LOX-1-dependent mechanism
por: Dong, Q., et al.
Publicado: (2013)

KAP1 silencing relieves OxLDL-induced vascular endothelial dysfunction by down-regulating LOX-1
por: Yan, Tianqing, et al.
Publicado: (2020)

Reducing the Damage of Ox-LDL/LOX-1 Pathway to Vascular Endothelial Barrier Can Inhibit Atherosclerosis
por: Guo, Xiaopeng, et al.
Publicado: (2022)

Ginkgolide B Reduces LOX-1 Expression by Inhibiting Akt Phosphorylation and Increasing Sirt1 Expression in Oxidized LDL-Stimulated Human Umbilical Vein Endothelial Cells
por: Ma, Lina, et al.
Publicado: (2013)

Forkhead box protein 1 transcriptionally activates sestrin1 to alleviate oxidized low-density lipoprotein-induced inflammation and lipid accumulation in macrophages
por: Gao, Feng, et al.
Publicado: (2022)

Dyslipidemia-Induced Neuropathy in Mice: The Role of oxLDL/LOX-1
por: Vincent, Andrea M., et al.
Publicado: (2009)

Pinoresinol Diglucoside Alleviates oxLDL-Induced Dysfunction in Human Umbilical Vein Endothelial Cells
por: Yao, Jinpeng, et al.
Publicado: (2016)

Albiflorin Alleviates Ox-LDL-Induced Human Umbilical Vein Endothelial Cell Injury through IRAK1/TAK1 Pathway
por: Liu, Yeling, et al.
Publicado: (2022)

Astragaloside IV protects endothelial progenitor cells from the damage of ox-LDL via the LOX-1/NLRP3 inflammasome pathway
por: Qian, Weibin, et al.
Publicado: (2019)

miR-155 Promotes ox-LDL-Induced Autophagy in Human Umbilical Vein Endothelial Cells
por: Zhang, Zhaozhi, et al.
Publicado: (2017)

Suppression of lncRNA Gm47283 attenuates myocardial infarction via miR-706/ Ptgs2/ferroptosis axis
por: Gao, Feng, et al.
Publicado: (2022)

Salidroside protects against ox-LDL-induced endothelial injury by enhancing autophagy mediated by SIRT1-FoxO1 pathway
por: Zhu, Zhongsheng, et al.
Publicado: (2019)

Expression of LOX-1 in human mesangial cells is increased by Ox-LDL and IL-1β treatment
por: Deng, Yinghui, et al.
Publicado: (2017)

Ginsenoside Rg1 ameliorates apoptosis, senescence and oxidative stress in ox-LDL-induced vascular endothelial cells via the AMPK/SIRT3/p53 signaling pathway
por: Lyu, Tian-Jiao, et al.
Publicado: (2022)

Shikonin Alleviates Endothelial Cell Injury Induced by ox-LDL via AMPK/Nrf2/HO-1 Signaling Pathway
por: Liu, Shuang, et al.
Publicado: (2021)

SIRT6 mediates MRTF-A deacetylation in vascular endothelial cells to antagonize oxLDL-induced ICAM-1 transcription
por: Huang, Shan, et al.
Publicado: (2022)

Concentration polarization of ox-LDL activates autophagy and apoptosis via regulating LOX-1expression
por: Ding, Zufeng, et al.
Publicado: (2013)

Interleukin-1β Promotes Ox-LDL Uptake by Human Glomerular Mesangial Cells via LOX-1
por: Liu, Hua, et al.
Publicado: (2020)

6-Shogaol Protects against Oxidized LDL-Induced Endothelial Injruries by Inhibiting Oxidized LDL-Evoked LOX-1 Signaling
por: Wang, Yun kai, et al.
Publicado: (2013)

LOX-1 Regulates P. gingivalis-Induced Monocyte Migration and Adhesion to Human Umbilical Vein Endothelial Cells
por: Li, Qian, et al.
Publicado: (2020)

Beneficial Effects of Ticagrelor on Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Apoptosis in Human Umbilical Vein Endothelial Cells
por: Kang, Meini, et al.
Publicado: (2019)

Myeloperoxidase-Oxidized LDL Activates Human Aortic Endothelial Cells through the LOX-1 Scavenger Receptor
por: El-Hajjar, Layal, et al.
Publicado: (2022)

The LOX-1 receptor ectopically expressed in the liver alleviates atherosclerosis by clearing Ox-LDL from the circulation
por: Wang, Zhiwen, et al.
Publicado: (2022)

Autophagic degradation of LOX-1 is involved in the maintenance of vascular integrity injured by oxLDL and protected by Berberine
por: Zheng, Yangmin, et al.
Publicado: (2023)

Mannose-Binding Lectin Reduces Oxidized Low-Density Lipoprotein Induced Vascular Endothelial Cells Injury by Inhibiting LOX1-ox-LDL Binding and Modulating Autophagy
por: Zhou, Xuelian, et al.
Publicado: (2023)

A fermented bean flour extract downregulates LOX-1, CHOP and ICAM-1 in HMEC-1 stimulated by ox-LDL
por: Gabriele, Morena, et al.
Publicado: (2016)

Rotigotine protects against oxidized low-density lipoprotein(ox-LDL)-induced damages in human umbilical vein endothelial cells(HUVECs)
por: Kang, Hui, et al.
Publicado: (2021)

Possible involvement of the oxLDL/LOX-1 system in the pathogenesis and progression of human intervertebral disc degeneration or herniation
por: Li, Xinhua, et al.
Publicado: (2017)

MicroRNA-98 rescues proliferation and alleviates ox-LDL-induced apoptosis in HUVECs by targeting LOX-1
por: Chen, Zhibo, et al.
Publicado: (2017)

Apremilast ameliorates ox-LDL-induced endothelial dysfunction mediated by KLF6
por: Wang, Hao, et al.
Publicado: (2020)

Oxidized LDL and LOX-1 in Experimental Sepsis
por: Al-Banna, Nadia, et al.
Publicado: (2013)

Mechanism of tacrolimus-induced chronic renal fibrosis following transplantation is regulated by ox-LDL and its receptor, LOX-1
por: Deng, Shi, et al.
Publicado: (2016)

C1q/TNF-Related Protein-9 Ameliorates Ox-LDL-Induced Endothelial Dysfunction via PGC-1α/AMPK-Mediated Antioxidant Enzyme Induction
por: Sun, Haijian, et al.
Publicado: (2017)

Sirt6-induced autophagy restricted TREM-1-mediated pyroptosis in ox-LDL-treated endothelial cells: relevance to prognostication of patients with acute myocardial infarction
por: Zi, Ye, et al.
Publicado: (2019)

Native and Oxidized Low-Density Lipoproteins Increase the Expression of the LDL Receptor and the LOX-1 Receptor, Respectively, in Arterial Endothelial Cells
por: Catar, Rusan, et al.
Publicado: (2022)

Molecular dynamics simulation of human LOX-1 provides an explanation for the lack of OxLDL binding to the Trp150Ala mutant
por: Falconi, Mattia, et al.
Publicado: (2007)

Liraglutide ameliorates oxidized LDL-induced endothelial dysfunction by GLP-1R-dependent downregulation of LOX-1-mediated oxidative stress and inflammation
por: Ying, Wu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_h7280h9m8g7rnhni47sme1pkje