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P2X7 receptor knockdown suppresses osteoclast differentiation by inhibiting autophagy and Ca(2+)/calcineurin signaling

Bone is continuously remodeled in a dynamic process maintained by osteoclasts and osteoblasts, and imbalances in the relative activities of these cell types can cause various pathological conditions, including rheumatoid arthritis and osteoporosis. Osteoclasts are multinucleated cells that serve an...

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Detalles Bibliográficos
Autores principales: Ma, Yonggang, Di, Ran, Zhao, Hongyan, Song, Ruilong, Zou, Hui, Liu, Zongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941524/
https://www.ncbi.nlm.nih.gov/pubmed/35266012
http://dx.doi.org/10.3892/mmr.2022.12677