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Evidence for ABL Amplification in Multiple Myeloma and Therapeutic Implications

BACKGROUND: Cytogenetic abnormalities are considered initiating events in the pathogenesis of multiple myeloma (MM) and are assumed to be of clinical significance. METHODS: Fluorescence in situ hybridization (FISH) was used to analyze chromosomal architecture in 101 patients with MM. We evaluated ov...

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Detalles Bibliográficos
Autores principales: Huang, He, Zhou, Shuping, Lin, Hongdou, Guo, Wenjian, Lin, Ying, Yao, Ronxin, He, Licai, Yu, Kang, Li, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941557/
https://www.ncbi.nlm.nih.gov/pubmed/35342415
http://dx.doi.org/10.1155/2022/4112016