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Sex-specific genetic modifiers identified susceptibility of cold stored red blood cells to osmotic hemolysis

BACKGROUND: Genetic variants have been found to influence red blood cell (RBC) susceptibility to hemolytic stress and affect transfusion outcomes and the severity of blood diseases. Males have a higher susceptibility to hemolysis than females, but little is known about the genetic mechanism contribu...

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Detalles Bibliográficos
Autores principales: Fang, Fang, Hazegh, Kelsey, Mast, Alan E., Triulzi, Darrell J., Spencer, Bryan R., Gladwin, Mark T., Busch, Michael P., Kanias, Tamir, Page, Grier P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941732/
https://www.ncbi.nlm.nih.gov/pubmed/35321643
http://dx.doi.org/10.1186/s12864-022-08461-4