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Lack of tumorigenesis and protumorigenic activity of human umbilical cord mesenchymal stem cells in NOD SCID mice

BACKGROUND: The tumorigenesis of infused umbilical cord mesenchymal stem cells (UC-MSCs) is being preclinically evaluated. METHODS: We observed tumor formation in NOD SCID mice after a single subcutaneous injection of hUC-MSCs and the effect of these cells on tumor growth in tumor-bearing mice. Thre...

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Detalles Bibliográficos
Autores principales: He, Jie, Yao, Xiang, Mo, Ping, Wang, Kai, Yang, Zai-ling, Tian, Ni-ni, Zhu, Xiang-qing, Zhao, Jing, Pang, Rong-qing, Ruan, Guang-ping, Pan, Xing-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941803/
https://www.ncbi.nlm.nih.gov/pubmed/35317758
http://dx.doi.org/10.1186/s12885-022-09431-5