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Using real-world data to dynamically predict flares during tapering of biological DMARDs in rheumatoid arthritis: development, validation, and potential impact of prediction-aided decisions

BACKGROUND: Biological disease-modifying antirheumatic drugs (bDMARDs) are effective in the treatment of rheumatoid arthritis. However, as bDMARDs may also lead to adverse events and are expensive, tapering them is of great clinical interest. Tapering according to disease activity-guided dose optimi...

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Detalles Bibliográficos
Autores principales: van der Leeuw, Matthijs S., Messelink, Marianne A., Tekstra, Janneke, Medina, Ojay, van Laar, Jaap M., Haitjema, Saskia, Lafeber, Floris, Veris-van Dieren, Josien J., van der Goes, Marlies C., den Broeder, Alfons A., Welsing, Paco M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941811/
https://www.ncbi.nlm.nih.gov/pubmed/35321739
http://dx.doi.org/10.1186/s13075-022-02751-8