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Stable Cell Clones Harboring Self-Replicating SARS-CoV-2 RNAs for Drug Screen

The development of antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been hampered by the lack of efficient cell-based replication systems that are amenable to high-throughput screens in biosafety level 2 laboratories. Here we report that stable cell clones harborin...

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Detalles Bibliográficos
Autores principales: Liu, Shufeng, Chou, Chao-Kai, Wu, Wells W., Luan, Binquan, Wang, Tony T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941906/
https://www.ncbi.nlm.nih.gov/pubmed/35080424
http://dx.doi.org/10.1128/jvi.02216-21