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The “LLQY” Motif on SARS-CoV-2 Spike Protein Affects S Incorporation into Virus Particles

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein mediates viral entry and membrane fusion. Its cleavage at S1/S2 and S2′ sites during the biosynthesis in virus producer cells and viral entry are critical for viral infection and transmission. In contrast, the biolog...

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Detalles Bibliográficos
Autores principales: Du, Shouwen, Xu, Wang, Wang, Yuhang, Li, Letian, Hao, Pengfei, Tian, Mingyao, Wang, Maopeng, Li, Tiyuan, Wu, Shipin, Liu, Quan, Bai, Jieying, Qu, Xiaoyun, Jin, Ningyi, Zhou, Boping, Liao, Ming, Li, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941915/
https://www.ncbi.nlm.nih.gov/pubmed/35045269
http://dx.doi.org/10.1128/jvi.01897-21