Contribution of Neuraminidase to the Efficacy of Seasonal Split Influenza Vaccines in the Ferret Model

Seasonal influenza vaccination takes into account primarily hemagglutinin (HA)-specific neutralizing antibody responses. However, the accumulation of substitutions in the antigenic regions of HA (i.e., antigenic drift) occasionally results in a mismatch between the vaccine and circulating strains. T...

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Detalles Bibliográficos
Autores principales: Rosu, Miruna E., Kok, Adinda, Bestebroer, Theo M., de Meulder, Dennis, Verveer, Elwin P., Pronk, Mark R., Dekker, Lennard J. M., Luider, Theo M., Richard, Mathilde, van den Brand, Judith M. A., Fouchier, Ron A. M., Herfst, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941921/
https://www.ncbi.nlm.nih.gov/pubmed/35107371
http://dx.doi.org/10.1128/jvi.01959-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941921/
https://www.ncbi.nlm.nih.gov/pubmed/35107371
http://dx.doi.org/10.1128/jvi.01959-21

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