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Targeted Deletion of Glycoprotein B Gene by CRISPR/Cas9 Nuclease Inhibits Gallid herpesvirus Type 3 in Dually Infected Marek’s Disease Virus-Transformed Lymphoblastoid Cell Line MSB-1

Marek’s disease virus (MDV) is a member of the genus Mardivirus in the subfamily Alphaherpesvirinae. There are three different serotypes of MDV designated as MDV-1 (Gallid herpesvirus type 2), MDV-2 (Gallid herpesvirus type 3), and MDV-3 (Meleagrid herpesvirus 1, herpesvirus of turkeys, HVT). MDV-1...

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Detalles Bibliográficos
Autores principales: Zhang, Yaoyao, Li, Weicheng, Tang, Na, Moffat, Katy, Nair, Venugopal, Yao, Yongxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941929/
https://www.ncbi.nlm.nih.gov/pubmed/35107377
http://dx.doi.org/10.1128/jvi.02027-21