Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens

Phylogenetically diverse bacteria can carry out chloramphenicol reduction, but only a single enzyme has been described that efficiently catalyzes this reaction, the NfsB nitroreductase from Haemophilus influenzae strain KW20. Here, we tested the hypothesis that some NfsB homologs function as houseke...

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Detalles Bibliográficos
Autores principales: Mullowney, Michael W., Maltseva, Natalia I., Endres, Michael, Kim, Youngchang, Joachimiak, Andrzej, Crofts, Terence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941942/
https://www.ncbi.nlm.nih.gov/pubmed/35195438
http://dx.doi.org/10.1128/spectrum.00139-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941942/
https://www.ncbi.nlm.nih.gov/pubmed/35195438
http://dx.doi.org/10.1128/spectrum.00139-22

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