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Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens
Phylogenetically diverse bacteria can carry out chloramphenicol reduction, but only a single enzyme has been described that efficiently catalyzes this reaction, the NfsB nitroreductase from Haemophilus influenzae strain KW20. Here, we tested the hypothesis that some NfsB homologs function as houseke...
Autores principales: | Mullowney, Michael W., Maltseva, Natalia I., Endres, Michael, Kim, Youngchang, Joachimiak, Andrzej, Crofts, Terence S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941942/ https://www.ncbi.nlm.nih.gov/pubmed/35195438 http://dx.doi.org/10.1128/spectrum.00139-22 |
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