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Eukaryotic TYW1 Is a Radical SAM Flavoenzyme
[Image: see text] TYW1 is a radical S-adenosyl-l-methionine (SAM) enzyme that catalyzes the condensation of pyruvate and N-methylguanosine-containing tRNA(Phe), forming 4-demethylwyosine-containing tRNA(Phe). Homologues of TYW1 are found in both archaea and eukarya; archaeal homologues consist of a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941971/ https://www.ncbi.nlm.nih.gov/pubmed/34184886 http://dx.doi.org/10.1021/acs.biochem.1c00349 |